Designers’ Row

Several streets claim to be "Designers' Row." All three can be justified. The block on East 58th Street (also East 59th Street), between Third and Second Avenues, has an official street sign.

http://www.nyblade.com/2005/6-24/locallife/Pride/ghetto.cfm
The original gay ghetto
By KEVIN SCOTT
Friday, June 24, 2005

Everyone has his or her favorite block in Manhattan. Mine is East 58th Street between Second and Third Avenues, "Designer's Row," as it's called these days.

More than just a block of design stores and antique shops, this one short block boasts four fine Indian restaurants, three of the last gay haunts on the East Side, several fancy Italian restaurants, and of course, a world of stores selling bathtubs, doorknobs and patio furniture to decorators and style-conscious amateurs.
(...)
"Designers Row" is a little oasis of gaydom in a neighborhood gone utterly hetero and high-rise.

http://www.bigapplestyle.net/events.html
It's early noon as I make my way into the heart of designer's row, 39th between 5th and 6th avenues. I'm just a block away from the fashion week tents, but my focus is to meet with a man behind the vision of "waist dressing", Christos Dovas.

26 January 1992, New York Times, pg. R1:
FILA SPORTS, the high-priced Italian sports clothes company, just opened its first New York boutique, at 831 Madison Avenue near 69th Street, in the heart of designer row.

2 April 1997, New York Times, pg. B5:
Santoni, a designer and manufacturer of handmade men's Italian shoes and accessories, is coming to Madison Avenue's designer's row. The company, based in Corridonia, Italy, has leased 1,800 square feet, at 864 Madison Avenue, between 70th and 71st Streets, for its first retail store in the United States.