“SoSo” is the “south of Southtown” neighborhood of San Antonio. The neighborhood nickname—like so many others—is inspired by New York City’s 1960s-era neighborhood nickname SoHo (South of Houston Street). “SoSo” has been used since at least 2006.
   
“So-so” means “average” or “not so great,” and the “SoSo” neighborhood nickname has had similar “so-so” reviews.
     
     
About.com: San Antonio
Central Loop - Downtown San Antonio
From Kori Ellis, for About.com
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Central Loop Districts and Neighborhoods:
Alamo District
Central Business District
Convention Center District
Historic Civic District
Houston Street District
Lavaca
River North
King William Historic District
La Villita District
Market Square District
NoDo (Northside of Downtown)
River Bend District
Southtown
SoSo (South of Southtown)
   
Wikipedia Talk: San Antonio, Texas
Actually, “Great Northwest” is the valid name for the neighborhood (a bunch of subdivisions) near Culebra and 1604, extending north toward the Medical Center (I used to live there). And “SoSo”, or “South of Southtown,” really is the name being frantically pushed (signs posted all over) by the people in that area. But you’re right, no one else seems to be using it, nor are many people using “Southtown” for that matter, even though the city has given the area that official designation. Crazed actor 19:21, 3 March 2006 (UTC)
 
7 April 2006, San Antonio (TX) Express-News, Weekender, pg. 14H:
The Red Room (8:30 pm)—The new listening room south of Southtown (in SoSo?) opened last weekend in fine style.
         
City-Data.com
210
08-19-2006, 07:42 PM
If anyone is interested in living downtown or Southtown or SoSo (South of Southtown) or SoFlo, let me know and I will help you out with information.
       
MySA.com
Arts area known by multiple names (September 6, 2006)
Nicole Lessin EXPRESS-NEWS STAFF WRITER   San Antonio Express-News (TX)
Neighbors - South/East Page 01SE (604 Words)
Depending on whom you ask, this quiet older neighborhood with an artistic flavor has different boundaries and even dissimilar names. It’s Roosevelt Park. It’s Southpark Meadows. It’s Riverside Park. It’s Shallow Southtown. It’s soSo (south of Southtown).
 
Some are not even sure. Others—even those who have lived and worked in the area for decades—don’t know.
 
“I call it that cool little neighborhood…”
 
City-Data.com
charmed4947
01-28-2007, 11:50 PM
Great article, thanks. Any pictures of SoFlo, SoSo or Southtown? Your other pictures of San Antonio are great. 
 
My RV Life
Sunday, March 2, 2008
San Antonio: From the eye of an accidental tourist.
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Downtown is home to many districts including the Alamo District, Alamodome District, Central Business District, Convention Center District, Historic Civic District, Houston Street District, King William Historic District, La Villita District, Market Square District, North Downtown, North River District, River Bend District, SoSo (South of Southtown), Southtown, and the University District.
San Antonio Express-News (TX)