Ozempic Face

         
Wikipedia: Semaglutide
Semaglutide is an anti-diabetic medication used for the treatment of type 2 diabetes, and an anti-obesity medication used for weight management. It can be administered by subcutaneous injection or taken orally. It is sold as a generic drug by several drug companies in the Indian and Canadian markets, and worldwide by its originator, Novo Nordisk, under the brand names Ozempic and Rybelsus for diabetes; under the brand name Wegovy for weight management; and under the brand names Wegovy and Kayshild for the treatment of metabolic-associated steatohepatitis (nonalcoholic steatohepatitis) and liver cirrhosis.
 
Town and Country
What is Ozempic Face?
Catherine Deneuve once remarked that, at a certain age, you need to choose between your derriere or your face. Those using semaglutide injections for weight loss may be confronted with the same dilemma.
By Jamie Rosen
Published: Nov 29, 2022 8:00 AM EST
 
Washingtonian 
An Actual Cool Person Weighs In on the Washington Post’s 2023 In/Out List
Baffled by many of the entries (“ozempic face”?), we called up a teenager.
Written by Sylvie McNamara | Published on December 30, 2022
(...)
Out: Ozempic face. In: Buccal fat pad removal
“I don’t know what ozempic face is, but buccal fat pad removal is a terrible idea. First of all, it’s literally going to ruin your face—you need that skin to look youthful. And then in two years the fat is going to be in again and you’re not going to have it. So you’re just preying on your own downfall.”
     
People
What Is Ozempic Face? Doctors Explain the Side Effect of the Diabetes Drug
Experts explain that taking medications like Ozempic and Wegovy, for type 2 diabetes and weight loss, can cause an aged appearance in the face
By Vanessa Etienne Published on January 24, 2023 05:20PM EST
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Dr. Paul Jarrod Frank, a dermatologist in New York, coined the term “Ozempic face” to describe this side effect, noting that it’s typically people in their 40s or 50s who are concerned about the sagging that occurs as a result of the weight loss in their face.
 
“I see it every day in my office,” Frank said. “A 50-year-old patient will come in, and suddenly, she’s super-skinny and needs filler, which she never needed before. I look at her and say, ‘How long have you been on Ozempic?’ And I’m right 100 percent of the time. It’s the drug of choice these days for the 1 percent.”
 
Fox News
‘Ozempic face?’ Dr. Siegel warns of popular diabetes drug’s bizarre side effect
Semaglutide injections like Ozempic saw ongoing shortages after becoming TikTok famous
By Taylor Penley Fox News
Published January 29, 2023 11:00am EST
(...)
“I spoke with some dermatologists about this yesterday,” Dr. Siegel said of “Ozempic face,” a bizarre side effect reported in Ozempic patients who claim the drug is making them look older. “It’s an overuse of the drug to where you lose weight too quickly. The buccal mucosa – the fat – leaves your face, and you become gaunt looking.”
 
JPRAS (Journal of Plastic, Reconstructive & Aesthetic Surgery)
Correspondence and Communications Volume 81 p97-98 June 2023
Ozempic face: A new challenge for facial plastic surgeons
Jing Qin Tay .(JavaScript must be enabled to view this email address)
I am writing to share my concerns about a new phenomenon, dubbed “Ozempic face” by the media, that has beleaguered the facial plastic surgery and dermatology communities. The term was initially coined by Paul Jarrod Frank, a cosmetic and celebrity dermatologist in the United States (U.S.).1 It is used to describe the sagging, gaunt appearance of the facial skin caused by the loss of facial fat secondary to rapid weight loss after taking Ozempic, also known as Semaglutide.1 Ozempic was initially approved for the treatment of type 2 diabetes but has recently gained popularity as a weight-loss drug, especially in the U.S. It works by mimicking a hormone that suppresses appetite and slows stomach emptying. Despite the fact that Ozempic can help people with obesity and diabetes improve their health and quality of life, it may also have undesirable effects on their facial appearance.1

 
Cleveland Clinic
March 5, 2025/Diet, Food & Fitness/Weight Loss
‘Ozempic Face’: What It Is and How To Avoid It
Rapid weight loss can change the way your face looks, bringing wrinkles, sagging skin and a gaunt appearance
(...)
What is ‘Ozempic face’?
“The term ‘Ozempic face’ refers to the changes in the face that can happen with rapid weight loss,” explains endocrinologist Vinni Makin, MD. “It’s characterized by gauntness, sunken cheeks, new wrinkles and loose skin on the face and neck.”
 
‘Ozempic face’ isn’t a side effect of the medication itself. Rather, it’s a side effect of the rapid weight loss the medication can bring.
 
This term first became popular on social media after a celebrity dermatologist used the term to refer to the way that Ozempic (generic name: semaglutide) affected some of his patients. But it’s not a medical term, and it’s probably not one you’ll hear your healthcare provider use. It’s also not limited to taking Ozempic.
   
CNN
July 30, 2025
‘Ozempic face’ may be driving a cosmetic surgery boom
By Oscar Holland
About two years ago, celebrity cosmetic dermatologist Dr. Paul Jarrod Frank noticed a new type of patient arriving at his New York practice. Amid an explosion in the number of Americans losing weight with drugs like Ozempic, he saw a “dramatic spike” in clients experiencing unwelcome side effects.
 
“Although they felt much better losing weight, in some ways they felt they looked older,” he said via a voice note. “And this was due to the loss of volume in their face.”
 
Frank started using the term “Ozempic face” — a label he believes he coined — to describe the phenomenon.