“They’re off!” is a famous starting call in horse racing. “My wife and daughter are leaving because of my obsession with horse racing. And they’re off!” was posted on Twitter by sickipediabot on January 4, 2012. The joke originated on the Sickipedia website.
   
     
Twitter
Tankslapper
@tankslapper
My wife and daughter are leaving because of my obsession with horse racing.
And they’re off!
1:31 PM - 4 Jan 2012
   
Twitter
Chig
@Chig01
My wife and kids are leaving because of my obsession with horse racing.
And they’re off!
1:39 PM - 4 Jan 2012
   
Twitter
sickipediabot
@sickipediabot
My wife and daughter are leaving because of my obsession with horse racing.
And they’re off!
6:32 PM - 4 Jan 2012
 
Twitter         
naj s
@naj_s
My wife and daughter are leaving me because of my obsession with horseracing.    AaaannnD they’re Off.
8:30 AM - 7 Jan 2012
 
11 January 2012, Daily Record (Glasgow, Scotland), “Joke of the Week” by Tam Cowan, pg. 13:
MY wife and daughter have threatened to leave me due to my obsession with horse racing. And they’re off!
 
Reddit—Jokes
My wife and daughter are leaving me because of my obsession with horse racing…
submitted January 26, 2018 by madazzahatter
“And they’re off!”
 
Reddit—Jokes
My wife and daughter are leaving me because of my obsession with horse racing…
submitted July 13, 2018 by keithasaurus
“And they’re off!”
 
Reddit—Dad Jokes
My wife and kids are leaving me because of my obsession with horse racing. (self.dadjokes)
submitted October 11, 2018 by porichoygupto
And they’re off!