An “uptowner” is someone who inhabits the “uptown” section (often, but not always, located to the north) of a geographical area. “Up-towners” was cited in print in 1827, when it referred to Providence, Rhode Island. A May 1844 citation of “up towners” referred to Manhattan.
Similar Manhattan geographic nicknames include “downtowner,” “East Sider” and “West Sider.”
(Oxford English Dictionary)
‘uptowner n. a person from ‘uptown’.
1924 H. Crane Let. 24 Jan. (1965) 171 It’s become fashionable for the high-hatted uptowners now to buy Matisse’s paintings.
1981 P. Mallory Killing Matter xii. 129 The area had..its own rough charm, but it was as remote as Mozambique..to your educated Uptowner.
18 April 1827, Literary Cadet and Rhode-Island Statesman (Providence, RI), pg. 1, col. 3:
THE BLUE POINTERS.—At the south western extremity of this town, there used to reside a distinct race of beings, ‘yclept Blue Pointers; and isolated as they were, their habits, manners and customs, varied very materially from those of their neighbours, the up-streeters, the up-towners, the down-towners, Ship-streeters, and up-hillers.
29 June 1835, The Adams Sentinel and General Advertiser (Gettysburg, PA), pg. 3, col. 5:
If they were caught below Market-street, they were in danger, in the Border wars of that day, of being pelted with brick-backs as up towners, or if above Market-street, they ran the same risk as being down towners. In truth between the up towners and down towners of that day, we well recollect, it was no easy matter fo a boy to escape a broken pate.
16 May 1844, New-York (NY) Commercial Advertiser, pg. 2, col. 6 ad:
All ye Wall Streeters,
PEARL STREETERS, UP TOWNERS AND DOWN TOWNERS, would it not be well for you to buy your stationary at SHEPARD’S where you can buy letter paper at 5d, 7d, 10d, 14d, and 18d per quire.
The Mysteries and Miseries of New York:
A Story of Real Life
By Ned Buntline
New-York, NY: Published by W. F. Burgess
She is one of our real up-towners; rich and very aristocratic!”
Fresh Leaves from the Diary of a Broadway Dandy
Edited by John Denison Vose
New York, NY: Bunnell & Price
Soon I went into a fashionable saloon, where I met three up-towners, who, when they saw a heavy roll of bank-bills, did actually inquire, with much impertinence, how I could spend so much money.
OCLC WorldCat record
Author: Donald Byrd
Publisher: Los Angeles, CA : Blue Note, 
Edition/Format: Music LP : Jazz : No Linguistic Content
Fancy free --
I love the girl --
The uptowner --